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Multivitamin and Mineral B-Complex and D3 All-in-One

Multivitamin All-In-One 120 Capsules (4 month supply)

£39.99 £24.99

  • Specifically designed natural multivitamin dietary supplement for ME/CFS and Fibromyalgia patients
  • Contains 19 vitamins and minerals
  • Contains a unique inbuilt vitamin D3 and vitamin B-complex
  • B vitamins help encourage energy production, immunity, nerve and brain function and cardiac health
  • Vitamin D3 encourages the growth and maintenance of healthy bones, teeth and muscles
  • FREE UK and Ireland shipping when you spend £30 or more. More details here

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Patients’ Own Multivitamin with B-Complex and D3

Specifically designed for Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia patients, Patients’ Own’s multivitamin is an all-in-one product containing 19 vitamins and minerals along with a unique inbuilt vitamin D3 and vitamin B-complex, making it much more convenient and cost effective than buying three individual products.

B vitamins are vital for energy production, immunity, nerve and brain function and cardiac health. They form one of the key pillars of treating Chronic Fatigue Syndrome and Fibromyalgia.

Recommended for those with chronic health conditions, our multivitamin dietary supplement for Chronic Fatigue Syndrome and Fibromyalgia patients also contains a high dose of vitamin D3. This vitamin is essential for the growth and maintenance of healthy bones, teeth and muscles, helps to combat fatigue and also reduces the frequency of colds and flu. Public Health England and the government’s Scientific Advisory Committee on Nutrition (SACN) now recommend that everyone take a vitamin D supplement.

The Patients’ Own multivitamin also deliberately excludes iron and copper, which can increase oxidative stress – a major problem in Chronic Fatigue Syndrome.

The following Chronic Fatigue Syndrome and Fibromyalgia specialists recommend multivitamin supplements for CFS: Dr Lapp, Dr Cheney, Dr Teitelbaum, Dr Downing-Orr and Dr Myhill.

The science behind Patients’ Own multivitamin

A high-quality multivitamin is essential for patients suffering from CFS or Fibromyalgia.

Vitamins and minerals are crucial in order to achieve good health. Clinical trials have found that a lack of vitamins is a risk factor for issues such as heart disease and strokes. A lack of vitamins is also considered to be a risk factor for cancer, some birth defects, osteoporosis and several other chronic health conditions. It is therefore recommended that all adults take vitamin supplements.

Chronic Fatigue Syndrome patients experience extra stressors such as immune dysfunction, poor absorption of nutrients caused by bowel infections and chronic inflammation, which mean that levels above the recommended daily allowance of vitamin are advisable to help the body compensate.

Studies have found that multivitamin and mineral supplementation significantly decreased fatigue, sleep disorders, autonomic nervous system symptoms, frequency and intensity of headaches and subjective feelings of infection in Chronic Fatigue Syndrome patients.

There are hundreds of scientific papers that show how deficiencies of vitamins and minerals can cause symptoms like those seen in Chronic Fatigue Syndrome or Fibromyalgia, and how supplementation can reduce these symptoms. Below is a selection that specifically studies Chronic Fatigue Syndrome or Fibromyalgia patients:

B-Vitamin supplementation is a key treatment for CFS 

B-Vitamins are a critical component of treating Chronic Fatigue Syndrome. Among their many vital functions, B-Vitamins help with energy production and the correct functioning of the nervous system – both problem areas in CFS. Patients’ Own Multivitamin has a built-in Vitamin B complex which means patients do not have to buy a separate supplement.

Folic acid and Vitamin B12 can lead to significant improvement in ME/CFS symptoms

A study published in Neurology in 1993 found that half of the ME/CFS patients are deficient in folic acid (folate). A 2006 study published in Arzneimittel-Forschung found 81% of the 58 ME/CFS patients evaluated experienced subjective improvement of their symptoms after treatment with folate. Another study found that an individual daily dose of oral folic acid may alleviate symptoms in a subgroup of patients with ME/CFS and Fibromyalgia.

In 2015, a group of Swedish researchers published their results from a study of the benefit of vitamin B12 and folic acid supplementation. They examined clinical data from 38 female patients with Chronic Fatigue Syndrome who had been on B12 injections at least once a week for six months and up to several years, all of whom expressed they had benefited from the treatment. All but one (93%) of the good responders were treated with methylcobalamin, the biologically active form of vitamin B12 used in Patients’ Own multivitamin. According to University Health News, the conclusion was that vitamin B12, combined with an individual daily dose of oral folic acid, may provide high enough blood levels of these compounds for safe and effective relief of fatigue and other symptoms in some individuals suffering from Chronic Fatigue Syndrome.

ME/CFS patients are deficient in key B-Vitamins 

In 1999, a trial was conducted on Chronic Fatigue Syndrome patients to assess the functional status for the B vitamins pyridoxine, riboflavin and thiamine in 12 vitamin-untreated Chronic Fatigue Syndrome patients and in 18 healthy controls matched for age and sex. For all three enzymes, values were lower in Chronic Fatigue Syndrome patients than in controls. The authors concluded that the “data provide preliminary evidence of reduced functional B vitamin status, particularly of pyridoxine, in Chronic Fatigue Syndrome patients.”

CFS and Fibro patients are deficient in Vitamin D and benefit from supplementation

It is now recommended that everybody in the general population takes a Vitamin D supplement. For chronic disease sufferers, like those with Chronic Fatigue Syndrome and Fibromyalgia, it is especially important. With Patients’ Own Multivitamin’s potent dose of Vitamin D, it is not necessary to buy a separate supplement.

ME/CFS patients have significantly lower levels of Vitamin D than the general population 

A small case series by Hock et al. (2000) reported that fatigue was reduced in four Chronic Fatigue Syndrome patients who were treated daily with vitamin D plus minerals and trace elements.

A 2009 study by Berkovitz et al. investigated whether vitamin D levels are lower in Chronic Fatigue Syndrome patients than in the general British population. They found that vitamin D levels in the sample of 221 Chronic Fatigue Syndrome patients were moderately to severely suboptimal. These levels were significantly lower than those of the general British population. They conclude that oral or intramuscular vitamin D supplementation should be considered for Chronic Fatigue Syndrome patients.

Studies frequently find that Fibromyalgia patients have low levels of Vitamin D

There are such a large number of studies which have found that Fibromyalgia patients are deficient in vitamin D that it is impractical to analyse them all here. However, a recent meta-analysis by Hsiao et al. analysed 12 studies (eight of which the patients were diagnosed with Fibromyalgia and the rest with Chronic Widespread Pain), comprising of 1854 patients and 7850 controls. The patient group showed a significantly higher risk of a long-term deficiency of vitamin D than the control group.

After analysing the results from a large number of trials, Karras et al. state that “supplementation with vitamin D seemed to be effective in ameliorating some of the symptoms that these patients experienced”. They go on to conclude that “vitamin D should be recommended in all Fibromyalgia patients at high risk of developing hypovitaminosis D like insufficient sun exposure, inadequate dietary intake, and obesity”.

Zinc levels are low in CFS and Fibro patients, and the lower the level, the more severe the symptoms

Maes et al. (2006) examined serum zinc concentrations in patients with chronic fatigue syndrome (ME/CFS) versus normal volunteers. They found that serum zinc was significantly lower in the Chronic Fatigue Syndrome patients than in the normal controls. The lower the level of serum zinc, the greater the severity of Chronic Fatigue Syndrome and subjective experience of infection. They also found that low serum zinc levels are related to signs of inflammation and defects in early T cell activation pathways. Maes et al. conclude that since zinc is a strong anti-oxidant, the “results further support the findings that Chronic Fatigue Syndrome is accompanied by increased oxidative stress and that these reports suggest that some patients with Chronic Fatigue Syndrome should be treated with specific antioxidants, including zinc supplements”.

Sendur et al. (2008) assessed whether zinc levels are lower in Fibromyalgia patients than in healthy controls. They discovered that patients have significantly lower levels of zinc and the lower the level, the more tender points a patient has.

Correction of low Vitamin E levels correlates with CFS remission

A study published in 2010 by Miwa et al. found serum vitamin E concentrations were significantly lower in the patients with chronic fatigue syndrome as compared with the control subjects, suggesting increased oxidative stress in the former. The low level of serum vitamin E was ameliorated during the remission phase as compared with the exacerbation phase in the patients with chronic fatigue syndrome, suggesting that increased oxidative stress may be involved in the pathogenesis of chronic fatigue syndrome and might also be directly related to the severity of the symptoms of chronic fatigue syndrome.


Active Ingredients

Other Ingredients

HPMC vegetarian capsule

Our Quality

All of our products are manufactured in the UK to GMP code of practice and ISO 9001 quality assurance certification.


The recommended dose of our multivitamin dietary supplement for Chronic Fatigue Syndrome and Fibromyalgia patients is one capsule per day or as advised by your specialist practitioner or doctor. For maximum absorption, take with food alongside Patients’ Own Fish Oil and Coenzyme Q10. The Multivitamin and D Ribose work synergistically when taken together. You should always check with your doctor or pharmacist before taking new supplements.


Brewer S, “The Essential Guide to Vitamins, Minerals and Herbal Supplements,” London: Constable and Robinson. 2010

Teitelbaum J, “From Fatigued to Fantastic,” London: Penguin Books Ltd. 2007

Maric D, et al., “Multivitamin mineral supplementation in patients with chronic fatigue syndrome,” Med Sci Monit. 2014 Jan 14;20:47-53. doi: 10.12659/MSM.889333

Heap L, et al., “Vitamin B status in patients with chronic fatigue syndrome,” J R Soc Med. 1999 Apr; 92(4): 183–185.

Regland B, et al., “Response to Vitamin B12 and Folic Acid in Myalgic Encephalomyelitis and Fibromyalgia,” PLoS One. 2015; 10(4): e0124648.

Lundell K, et al., “Clinical activity of folinic acid in patients with chronic fatigue syndrome,” Arzneimittel-Forschung. 2006;56(6):399-404.

Jacobson W, et al., “Serum folate and chronic fatigue syndrome,” Neurology. 1993 Dec;43(12):2645-7.

Hsiao M.Y, et al., “Is serum hypovitaminosis D associated with chronic widespread pain including fibromyalgia? A meta-analysis of observational studies,” Pain Phys. 2015;18:E877–E887

Karras S, et al., “Vitamin D in Fibromyalgia: A Causative or Confounding Biological Interplay?,” Nutrients. 2016 Jun; 8(6): 343

Miwa K, et al., “Fluctuation of serum vitamin E (alpha-tocopherol) concentrations during exacerbation and remission phases in patients with chronic fatigue syndrome,” Heart Vessels. 2010 Jul;25(4):319-23. doi: 10.1007/s00380-009-1206-6.

Maes M, et al., “Lower serum zinc in Chronic Fatigue Syndrome (CFS): relationships to immune dysfunctions and relevance for the oxidative stress status in CFS,J Affect Disord. 2006 Feb;90(2-3):141-7. Epub 2005 Dec 9

Sendur OF., et al. “The relationship between serum trace element levels and clinical parameters in patients with fibromyalgia,” Rheumatol Int. 2008 Sep;28(11):1117-21.

Berkovitz S, et al., “Serum 25-hydroxy vitamin D levels in chronic fatigue syndrome: a retrospective survey,” Int J Vitam Nutr Res. 2009 Jul;79(4):250-4. doi: 10.1024/0300-9831.79.4.250.


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