Patients’ Own NADH
NADH, which stands for ‘nicotinamide adenine dinucleotide (NAD) + hydrogen (H)’, is a chemical which occurs naturally in the body and also plays a vital role in the chemical process that produces energy.
Taking an NADH supplement can improve memory, mental clarity, alertness and concentration.
NADH is predominantly used for treating Chronic Fatigue Syndrome, because of the role it plays in energy production.
The following Chronic Fatigue Syndrome specialists recommend taking NADH: Dr Lapp, The University of Maryland Medical Center, Dr Teitelbaum, Dr Podell and Dr Myhill.
The Science behind NADH’s use in CFS and Fibro
NADH is one of the most widely researched and successful treatments available to Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia patients particularly for reducing fatigue and increasing physical functioning.
NADH and CoQ10 work synergistically to reduce CFS symptoms
Castro-Marrero et al. found that NADH combined with Coenzyme Q10 significantly improved fatigue compared with a placebo group. In addition, a recovery of the biochemical parameters was also reported. all biochemical benchmarks improved in the treated group. The study was an 8-week, randomized, double-blind placebo-controlled trial using 73 Spanish Chronic Fatigue Syndrome patients.
A study published in Clinical Nutrition in 2016 assessed whether NADH and Coenzyme Q10 supplementation resulted in a significant reduction in maximum heart rate after a cycle test. The 8-week, randomized, controlled, double-blind trial was conducted on 80 ME/CFS patients. The CoQ10 and NADH group showed a significant reduction in max heart rate during a cycle ergometer test at week 8 versus baseline. Perception of fatigue also decreased through all follow-up visits in active group versus placebo.
NADH can reduce anxiety and improve physical functioning
Alegre J. et al. 2010 assessed the benefit of supplementing 77 Chronic Fatigue Syndrome patients with 20mg of NADH versus placebo in a three month long double blind, placebo controlled clinical trial. The investigators discovered that NADH significantly reduced anxiety levels and reduced maximum heart rate after a stress test suggesting NADH may help with post-exertional fatigue.
In 1999, the Department of Pediatrics at Georgetown University conducted a randomized, double-blind, placebo-controlled crossover study on patients with ME/CFS to evaluate the efficacy of NADH. Within the cohort of 26 patients, 8 of 26 (31%) responded favourably to NADH in contrast to 2 of 26 (8%) to placebo.
Santaella M., et al. (2004) compared NADH supplementation with conventional methods of treatment for patients with Chronic Fatigue Syndrome. A total of 31 patients fulfilling the Centers for Disease Control criteria for ME/CFS, were randomly assigned to either NADH or nutritional supplements and psychological therapy for 24 months. The twelve patients who received NADH had a dramatic and statistically significant reduction of symptoms.