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Turmeric with Piperine 500mg (180 capsules) - Patients' Own Nutrition
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Turmeric with Piperine 500mg (180 capsules)

£29.99 £19.99

  • Anti-inflammatory
  • Taking a Turmeric supplement for ME/CFS or Fibromyalgia can boost liver function and support liver regeneration
  • Helps to lower cholesterol levels
  • Relieves bloating and indigestion
  • Increases bile flow
  • Reduces blood clotting
  • FREE UK and Ireland shipping when you spend £30 or more. More details here

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Description

Patients’ Own Turmeric with Piperine

Turmeric is a well-researched, well-respected anti-inflammatory that helps to boost liver function and support liver regeneration.

Taking a Turmeric supplement for Chronic Fatigue Syndrome or Fibromyalgia can lower cholesterol levels, relieve bloating and indigestion, increase bile flow and reduce blood clotting.

Whilst Turmeric is very difficult to absorb on its own, the addition of black pepper extract included in our specialist Turmeric supplement for Chronic Fatigue Syndrome and Fibromyalgia makes it highly absorbable, ensuring your body receives all the health benefits of this active ingredient.

The Chronic Fatigue Syndrome specialists Dr Pall and Dr Myhill both recommend taking a Turmeric dietary supplement for ME/CFS.

The science behind treating CFS and Fibro with turmeric

Turmeric reduces inflammation in CFS and Fibro patients

With increased inflammation a common finding in Chronic Fatigue Syndrome and Fibromyalgia patients, it is turmeric’s anti-inflammatory qualities which are of particular interest.

According to Gupta et al. (2012), the curcumin, found in turmeric, modulate numerous signalling molecules such as pro-inflammatory cytokines (and many others) in human participants. Numerous high profile studies have implicated inflammatory cytokines as a major cause of the symptoms seen in CFS patients.

Gupta et al. (2009) evaluated the effect of curcumin in a mouse model of immunologically induced fatigue using a chronic water-immersion stress test. The mice showed significant increase in inflammation (TNF-alpha) levels. Concurrent treatment with curcumin resulted in significantly decreased inflammation. The authors conclude that the findings strongly suggest that during immunological activation, there is significant increase in oxidative stress and turmeric can be a valuable option in the treatment of Chronic Fatigue Syndrome.

Turmeric can restore HPA functioning in ME and Fibromyalgia patients

Another common finding in Chronic Fatigue Syndrome is hypothalamic-pituitary-adrenal (HPA) axis dysfunction which includes enhanced corticosteroid-induced negative feedback, basal hypocortisolism, attenuated diurnal variation, and a reduced responsivity to challenge (Tomas et al. 2013). Evidence suggests curcumin (an ingredient in turmeric) may restore proper functioning of the HPA axis.

Jithendra and Murthy (2011) investigated whether turmeric is effective in the treatment of posttraumatic stress disorder (PTSD) and on cortisol levels. They discovered that cortisol levels were increased significantly on long term treatment with curcumin. There was a decrease in the anxiety index and freezing response which indicated the therapeutic potential of curcumin for treating PTSD. Further, the increased cortisol levels reinforced the restoration of HPA-axis function, which normally becomes dysfunctional in PTSD.

Turmeric improves exercise performance and reduces physical fatigue

As well as being an effective anti-inflammatory and HPA modulator, turmeric appears to improve exercise performance and physical fatigue, a common problem in both Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia.

Huang et al. (2015) evaluated the potential beneficial effects of turmeric supplementation on fatigue and physical performance function following physical challenge in mice. Turmeric supplementation improved performance and fatigue, and the higher the dose, the greater the improvement. Muscular glycogen content, an important energy source for exercise, was significantly increased. The authors conclude that supplementation may have a wide spectrum of bioactivities for promoting health, improving exercise performance and preventing fatigue.

 

Ingredients

Active Ingredients

Organic Turmeric Powder 500mg

Black Pepper Extract (95% Piperine) 7.5mg

Other Ingredients

HPMC vegetarian capsule

Our Quality

All of our products are manufactured in the UK to GMP code of practice and ISO 9001 quality assurance certification.

Directions

The recommended dose for Chronic Fatigue Syndrome and Fibromyalgia is one capsule per day or as advised by your specialist practitioner or doctor. Turmeric is best absorbed with a fatty meal or oil such as Patients’ Own Omega 3 fish oil

References

A detailed table summarising completed trials with turmeric can be found here:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535097/table/Tab1/

Molecular targets of curcumin in human participants can be found here:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535097/table/Tab2/

Brewer S, “The Essential Guide to Vitamins, Minerals and Herbal Supplements,” London: Constable and Robinson. 2010

Gupta S., et al. “Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials.” American Association of Pharmaceutical Scientists 2013 Jan; 15(1): 195–218. Published online 2012 Nov 10. doi:  10.1208/s12248-012-9432-8

Gupta A., et al. “Curcumin, a polyphenolic antioxidant, attenuates chronic fatigue syndrome in murine water immersion stress model.” Immunobiology. 2009;214(1):33-9. doi: 10.1016/j.imbio.2008.04.003. Epub 2008 Jun 17.

Tomas C., et al. “A Review of Hypothalamic-Pituitary-Adrenal Axis Function in Chronic Fatigue Syndrome.” ISRN Neuroscience. 2013; 2013: 784520. Published online 2013 Sep 30. doi:  10.1155/2013/784520

Jithendra C. and Murthy T. “Restoration of Hypothalamic-Pituitary-Adrenal Axis Function in Rescue of Posttraumatic Stress Disorder in Curcumin-Treated Rats.” Biomedicine International Journals. 2011; 2: 72-80.

Huang WC., et al. “Effect of curcumin supplementation on physiological fatigue and physical performance in mice.” Nutrients. 2015 Jan 30;7(2):905-21. doi: 10.3390/nu7020905.

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